Authors: Cristoph Semken and David Rossell
Journal of the Royal Statistical Society. Series C: Applied Statistics, Vol. 71, No 5, 1330–1355, November, 2022A key issue in science is assessing robustness to data analysis choices, while avoiding selective reporting and providing valid inference. Specification Curve Analysis is a tool intended to prevent selective reporting. Alas, when used for inference it can create severe biases and false positives, due to wrongly adjusting for covariates, and mask important treatment effect heterogeneity. As our motivating application, it led an influential study to conclude there is no relevant association between technology use and teenager mental well-being. We discuss these issues and propose a strategy for valid inference. Bayesian Specification Curve Analysis (BSCA) uses Bayesian Model Averaging to incorporate covariates and heterogeneous effects across treatments, outcomes and subpopulations. BSCA gives significantly different insights into teenager well-being, revealing that the association with technology differs by device, gender and who assesses well-being (teenagers or their parents).